Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683318 | 0.79 | DPP4 (0.72) | DPP4 | |
| SCHEMBL19538192 | 0.73 | DPP4 (0.58) | DPP4NISCHKMT2AALDH1A1KDM4E | |
| SCHEMBL29597873 | 0.73 | NISCH (0.51) | DPP4NISCHKMT2AALDH1A1KDM4E | |
| SCHEMBL28968552 | 0.72 | DPP4 (0.47) | DPP4NISCHALDH1A1KDM4EHTT | |
| SCHEMBL12203811 | 0.71 | NISCH (0.50) | DPP4NISCHKMT2AALDH1A1KDM4E | |
| SCHEMBL24101388 | 0.66 | DPP4 (1.00) | DPP4 | |
| SCHEMBL19313444 | 0.66 | DPP4 (1.00) | DPP4 | |
| SCHEMBL19515148 | 0.66 | DPP4 (1.00) | DPP4 | |
| SCHEMBL19305509 | 0.66 | DPP4 (1.00) | DPP4 | |
| SCHEMBL415460 | 0.63 | NPSR1 (0.68) | KMT2APOLBHTTCYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801088-B | Benzo six-membered ring derivative and application thereof | 山东百极地长制药有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113801088-A | Benzo-six-membered ring derivative and application thereof | 山东百极地长制药有限公司 | 2021-12-17 | — | — | CN | disclosed |