Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21214538 | 0.79 | CYP19A1 (0.55) | DPP4KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL19313357 | 0.76 | MTNR1A (0.61) | DPP4 | |
| SCHEMBL5583686 | 0.75 | MAPT (0.43) | KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL5584234 | 0.75 | MAPT (0.43) | KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL5583735 | 0.75 | MAPT (0.43) | KDM4EMAPTHTTCYP1A2 | |
| Hydrochloric Acid SCHEMBL5586785 | 0.74 | HTR1A (0.42) | KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL22135584 | 0.74 | DPP4 (0.55) | DPP4KDM4EALDH1A1SIRT1SIRT2 | |
| SCHEMBL12203811 | 0.72 | NISCH (0.50) | DPP4KDM4EMAPTALDH1A1HTT | |
| SCHEMBL28677484 | 0.72 | DPP4 (0.49) | DPP4KDM4EANPEPCYP19A1ALDH1A1 | |
| SCHEMBL19538192 | 0.71 | DPP4 (0.58) | DPP4KDM4EALDH1A1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240586-B | 2,3-dihydro-1H-benzo [ f ] chroman-2-amine derivatives and their preparation | 山东百极地长制药有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-110240586-B | 2,3-dihydro-1H-benzo [ f ] chroman-2-amine derivatives and their preparation | 山东百极地长制药有限公司 | 2023-01-24 | — | — | CN | disclosed |