Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 13/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919869 | 0.78 | HPGD (0.49) | HPGDGAAALDH1A1MAPK1LMNA | |
| SCHEMBL7549991 | 0.77 | ALDH1A1 (0.52) | HPGDGAAALDH1A1MAPK1LMNA | |
| SCHEMBL19022012 | 0.76 | GLS (0.47) | LMNATSHR | |
| SCHEMBL8429681 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HTTKDM4E | |
| SCHEMBL7530193 | 0.71 | HPGD (0.71) | HPGDGAAPOLBTSHRHTT | |
| SCHEMBL463115 | 0.71 | — | — | |
| SCHEMBL2876964 | 0.71 | — | — | |
| SCHEMBL7324404 | 0.71 | ALDH1A1 (0.50) | HPGDALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL27807834 | 0.70 | KMT2A (0.50) | GAAALDH1A1MAPTPOLBHTT | |
| SCHEMBL10390356 | 0.70 | TDP1 (0.43) | HPGDGAAALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811305-A | Charged ion channel blockers and methods of use thereof | 诺西恩医疗公司 | 2021-12-17 | — | — | CN | disclosed |