Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | GSK3B | P49841 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515304 | 0.89 | GSK3B (0.62) | ALDH1A1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL15966835 | 0.86 | ALDH1A1 (1.00) | ALDH1A1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL28519313 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL28511432 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL11372872 | 0.83 | GSK3B (0.57) | ALDH1A1GSK3BMEN1KMT2A | |
| SCHEMBL28511846 | 0.81 | KDM4E (0.68) | ALDH1A1MEN1KMT2APTGER4KDM4E | |
| SCHEMBL7435419 | 0.80 | KDM4E (0.72) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL28678706 | 0.79 | KMT2A (0.55) | ALDH1A1GSK3BMEN1KMT2AKDM4E | |
| SCHEMBL11379590 | 0.78 | GSK3B (0.60) | GSK3BMEN1KMT2AKDM4ELMNA | |
| SCHEMBL15966782 | 0.78 | GSK3B (1.00) | GSK3BMEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041306-B | 4-hydroxy-2-quinolone-N- (4-quinazolinone) -3-carboxamide derivatives | 中国医学科学院药物研究所 | 2022-01-11 | — | — | CN | disclosed |