Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455129 | 0.81 | KDM4E (0.64) | KMT2AMEN1MAPTLMNACYP1A2 | |
| SCHEMBL28519313 | 0.80 | ALDH1A1 (0.58) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL28677828 | 0.79 | ALDH1A1 (0.75) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL28511432 | 0.79 | ALDH1A1 (0.54) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL148001 | 0.78 | MAPT (0.85) | KMT2AMEN1MAPTLMNACYP1A2 | |
| SCHEMBL29539965 | 0.78 | MAPT (0.85) | KMT2AMEN1MAPTLMNACYP1A2 | |
| SCHEMBL16516273 | 0.77 | MAPT (0.58) | KMT2AMEN1MAPTLMNACYP1A2 | |
| SCHEMBL22463722 | 0.77 | EGFR (0.54) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL28511846 | 0.77 | KDM4E (0.68) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL7999867 | 0.76 | CYP1A2 (0.57) | KMT2AMEN1MAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041306-B | 4-hydroxy-2-quinolone-N- (4-quinazolinone) -3-carboxamide derivatives | 中国医学科学院药物研究所 | 2022-01-11 | — | — | CN | disclosed |