Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740551 | 0.76 | MEN1 (0.58) | MEN1KMT2ATSHRKDM4CL3MBTL1 | |
| SCHEMBL1631295 | 0.72 | MEN1 (0.44) | MEN1KMT2AKDM4CL3MBTL1 | |
| SCHEMBL13572547 | 0.72 | KMT2A (0.58) | MEN1KMT2AKDM4C | |
| SCHEMBL1631504 | 0.72 | MEN1 (0.44) | MEN1KMT2ATSHRCNR2KDM4C | |
| SCHEMBL15765736 | 0.70 | RXRA (0.52) | MEN1KMT2APTGDR2RXRARXRB | |
| SCHEMBL28678179 | 0.69 | MEN1 (0.47) | MEN1KMT2AKDM4CL3MBTL1KDM4E | |
| SCHEMBL28664006 | 0.69 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL21326182 | 0.69 | CHRM2 (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL10705365 | 0.69 | KMT2A (0.52) | MEN1KMT2ATSHR | |
| SCHEMBL13736496 | 0.69 | KMT2A (0.52) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922437-B | Bridged piperidine derivatives | 豪夫迈·罗氏有限公司 | 2021-12-10 | — | — | CN | disclosed |