Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2682423 | 0.74 | TSHR (0.39) | KCNN4TSHRKDM4ECYP1A2TAAR1 | |
| SCHEMBL29184899 | 0.72 | CYP2C19 (0.39) | KCNN4TSHRKDM4ECYP1A2CYP2C19 | |
| SCHEMBL453393 | 0.72 | KCNN4 (0.52) | KCNN4TSHRKDM4EPOLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL10685401 | 0.70 | KCNN4 (0.50) | KCNN4TSHRKDM4EPOLBCYP1A2 | |
| SCHEMBL11651682 | 0.70 | KCNN4 (0.50) | KCNN4TSHRCYP1A2TAAR1CYP2D6 | |
| SCHEMBL6047551 | 0.70 | KCNN4 (0.50) | KCNN4TSHRKDM4EPOLBCYP1A2 | |
| SCHEMBL2790361 | 0.70 | KCNN4 (0.50) | KCNN4TSHRKDM4EPOLBCYP1A2 | |
| SCHEMBL1456007 | 0.69 | TAAR1 (0.50) | KCNN4KDM4EPOLBCYP1A2TAAR1 | |
| SCHEMBL744277 | 0.69 | TAAR1 (0.50) | KCNN4KDM4EPOLBCYP1A2TAAR1 | |
| SCHEMBL1455824 | 0.69 | TAAR1 (0.50) | KCNN4KDM4EPOLBCYP1A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385806-A | Process for the preparation of trimebutine and trimebutine maleate | 山西双雁药业有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-115385806-A | Process for the preparation of trimebutine and trimebutine maleate | 山西双雁药业有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-113999126-A | Preparation method of trimebutine | 浙江东亚药业股份有限公司 | 2022-02-01 | — | — | CN | disclosed |