Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142199 | 0.90 | USP2 (0.36) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL4834776 | 0.84 | ALDH1A1 (0.43) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL18342537 | 0.79 | MAPT (0.49) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL27545815 | 0.79 | TSHR (0.41) | ALDH1A1HPGDPRKCA | |
| SCHEMBL28202021 | 0.79 | GRIK1 (0.33) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL15689848 | 0.77 | FAAH (0.39) | GALR3ALDH1A1PRKCA | |
| SCHEMBL15645172 | 0.77 | FAAH (0.39) | GALR3ALDH1A1PRKCA | |
| SCHEMBL111270 | 0.77 | FAAH (0.39) | GALR3ALDH1A1PRKCA | |
| SCHEMBL27932297 | 0.77 | ALDH1A1 (0.46) | LMNAPDE4DALDH1A1 | |
| SCHEMBL10597517 | 0.77 | ABCC4 (0.43) | MAPTLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031630-A | Synthesis method of spiro thiophene sulfonamide compound | 福州大学 | 2022-02-11 | — | — | CN | claimed |
| CN-114031630-A | Synthesis method of spiro thiophene sulfonamide compound | 福州大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-114031630-A | Synthesis method of spiro thiophene sulfonamide compound | 福州大学 | 2022-02-11 | — | — | CN | disclosed |