Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673502 | 1.00 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL30968268 | 0.91 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL24714794 | 0.89 | RIPK1 (0.43) | RIPK1 | |
| SCHEMBL29455152 | 0.85 | NTRK1 (0.43) | RIPK1 | |
| SCHEMBL22644557 | 0.85 | NTRK1 (0.43) | RIPK1 | |
| SCHEMBL22638909 | 0.85 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL22638985 | 0.83 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL22638855 | 0.83 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL28682494 | 0.82 | RIPK1 (0.54) | RIPK1 | |
| SCHEMBL28677208 | 0.82 | RIPK1 (0.54) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767092-A | Bis-heterocyclic carbonyl substituted dihydropyrazole compound, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2021-12-07 | — | — | CN | disclosed |