Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 17/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678669 | 0.91 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL28673502 | 0.91 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL24714794 | 0.88 | RIPK1 (0.43) | RIPK1NTRK1 | |
| SCHEMBL22638909 | 0.86 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL22644557 | 0.84 | NTRK1 (0.43) | RIPK1NTRK1 | |
| SCHEMBL29455152 | 0.84 | NTRK1 (0.43) | RIPK1NTRK1 | |
| SCHEMBL22638829 | 0.82 | RIPK1 (0.41) | RIPK1NTRK1JAK2 | |
| SCHEMBL29730092 | 0.82 | RIPK1 (0.41) | RIPK1NTRK1JAK2 | |
| SCHEMBL22638897 | 0.81 | NR1H2 (0.39) | RIPK1NTRK1JAK2 | |
| SCHEMBL22638804 | 0.81 | NR1H2 (0.39) | RIPK1NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767092-B | Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine | 劲方医药科技(上海)有限公司 | 2024-07-16 | — | — | CN | disclosed |