Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699199 | 0.93 | HTT (0.40) | HTTCRHR1GAASMN1; SMN2NAMPT | |
| SCHEMBL17202434 | 0.85 | HTT (0.33) | HTTGAASMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL24506914 | 0.80 | SLC34A1 (0.46) | NAMPTHDAC1SLC34A1 | |
| SCHEMBL2364148 | 0.78 | HTT (0.44) | HTTGAASMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL24507073 | 0.76 | SLC34A1 (0.43) | NAMPTHDAC1SLC34A1 | |
| SCHEMBL17202438 | 0.75 | DPP4 (0.39) | HTTGAASMN1; SMN2NAMPTHDAC1 | |
| SCHEMBL24507072 | 0.75 | SLC34A1 (0.42) | NAMPTHDAC1HPGDENPP2SLC34A1 | |
| SCHEMBL28383936 | 0.73 | HTT (0.38) | HTTCRHR1GAASMN1; SMN2TSHR | |
| SCHEMBL19005685 | 0.72 | ESR2 (0.46) | CRHR1SMN1; SMN2SLC34A1 | |
| SCHEMBL28703394 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113891891-A | Modulators of AMPA receptor signaling | 戒毒及精神健康中心 | 2022-01-04 | — | — | CN | disclosed |