Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678787 | 0.93 | HTT (0.37) | HTTGAAENPP2RAB9AHPGD | |
| SCHEMBL24507072 | 0.82 | SLC34A1 (0.42) | ENPP2HPGDNAMPT | |
| SCHEMBL17202434 | 0.82 | HTT (0.33) | HTTGAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL24507073 | 0.80 | SLC34A1 (0.43) | NAMPT | |
| SCHEMBL24506914 | 0.74 | SLC34A1 (0.46) | NAMPT | |
| SCHEMBL2364148 | 0.74 | HTT (0.44) | HTTGAARAB9AHPGDTSHR | |
| SCHEMBL17202602 | 0.74 | SLC6A9 (0.45) | NAMPT | |
| SCHEMBL17202438 | 0.72 | DPP4 (0.39) | HTTGAATSHRNAMPTALDH1A1 | |
| SCHEMBL2364142 | 0.71 | DPP4 (0.41) | NAMPT | |
| SCHEMBL15152954 | 0.71 | DPP4 (0.39) | HTTGAATSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113891891-A | Modulators of AMPA receptor signaling | 戒毒及精神健康中心 | 2022-01-04 | — | — | CN | disclosed |