SCHEMBL28679029

SCHEMBL28679029

COc1ccc(/C=C/C(=O)c2ccc(OCC(=O)NC3CCN(Cc4ccccc4)CC3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADIPOR2 Q86V24 1/20 0.67
ADIPOR1 Q96A54 1/20 0.67
USP2 O75604 1/20 0.67
POLB P06746 1/20 0.66
SIGMAR1 Q99720 5/20 0.62
ACHE P22303 3/20 0.58
FAAH O00519 1/20 0.58
MAOB P27338 1/20 0.57
BCHE P06276 2/20 0.56
DRD2 P14416 1/20 0.55
HTR2A P28223 1/20 0.55
HTR2C P28335 1/20 0.55
HTR2B P41595 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28679030 1.00 ADIPOR2 (0.67) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28683097 1.00 ADIPOR2 (0.67) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28683100 1.00 ADIPOR2 (0.67) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28677883 0.94 ADIPOR2 (0.73) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28677884 0.94 ADIPOR2 (0.73) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28683173 0.94 ADIPOR2 (0.73) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28685671 0.93 ADIPOR2 (0.65) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28685673 0.93 ADIPOR2 (0.65) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28679280 0.93 ADIPOR2 (0.67) ADIPOR2ADIPOR1USP2POLBSIGMAR1
SCHEMBL28679281 0.93 ADIPOR2 (0.67) ADIPOR2ADIPOR1USP2POLBSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107686463-B Chalcone aryloxy acetamide compound, preparation method and application thereof 安徽中医药大学 2022-02-01 CN disclosed