Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.65 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28685671 | 1.00 | ADIPOR2 (0.65) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28683100 | 0.93 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28683097 | 0.93 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28679029 | 0.93 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28679030 | 0.93 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28683173 | 0.90 | ADIPOR2 (0.73) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28703775 | 0.89 | ADIPOR2 (0.62) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28703776 | 0.89 | ADIPOR2 (0.62) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28677884 | 0.89 | ADIPOR2 (0.73) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 | |
| SCHEMBL28677883 | 0.89 | ADIPOR2 (0.73) | ADIPOR2ADIPOR1USP2POLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107686463-B | Chalcone aryloxy acetamide compound, preparation method and application thereof | 安徽中医药大学 | 2022-02-01 | — | — | CN | disclosed |