SCHEMBL28679199

SCHEMBL28679199

CC(=O)C(C(C)=O)c1ccncc1.CC(=O)C(C(C)=O)c1ccncc1.[Cu]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
TP53 P04637 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CYP19A1 P11511 3/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
PTGS2 P35354 1/20 0.37
ALDH1A1 P00352 3/20 0.37
MDM2 Q00987 1/20 0.37
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
EPHX1 P07099 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP17A1 P05093 4/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824408 0.98 CYP3A4 (0.43) CYP3A4CYP2C19TP53NAPRTSLC6A2
SCHEMBL11458883 0.80 BRD4 (0.44) PTGS2ALDH1A1TSHRMAPK1KDM4E
SCHEMBL28718502 0.79 CYP3A4 (0.33) CYP3A4CYP2C19TP53NAPRTCYP19A1
SCHEMBL27566422 0.79 HSD17B10 (0.42) CYP3A4CYP2C19SLC6A3CYP19A1ALDH1A1
SCHEMBL23832254 0.79 MMP8 (0.47) CYP19A1ALDH1A1TSHRKDM4EHSD17B10
SCHEMBL11879035 0.77 CYP19A1 (0.49) CYP3A4CYP2C19TP53NAPRTCYP19A1
SCHEMBL23555481 0.77 ROCK2 (0.42) CYP3A4CYP2C19TP53NAPRTSLC6A2
SCHEMBL7269087 0.77 CYP3A4 (0.41) CYP3A4CYP2C19TP53NAPRTSLC6A2
SCHEMBL306354 0.76 CA1 (0.44) CYP3A4CYP2C19NAPRTSLC6A2SLC6A4
SCHEMBL8062050 0.76 SRC (0.61) CYP3A4CYP2C19NAPRTSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114828999-A Gas storage materials containing metal-organic structures bound via hydroxamic acids 学校法人立教学院 2022-07-29 CN disclosed
CN-114072454-A Metal-organic structure having terephthalic acid-based ligand 学校法人立教学院 2022-02-18 CN disclosed
CN-113811525-A Metal organic structure 学校法人立教学院 2021-12-17 CN disclosed