Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678769 | 0.86 | ALDH1A1 (0.47) | KDM4EMAPTSMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL29362495 | 0.86 | ALDH1A1 (0.47) | KDM4EMAPTSMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL14416135 | 0.73 | CES1 (0.52) | KDM4EMAPK1CYP3A4PKMKMT2A | |
| SCHEMBL5936894 | 0.73 | SRD5A2 (0.59) | KDM4EMAPTSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL29851576 | 0.71 | ALDH1A1 (0.59) | KDM4EMAPTSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL5080927 | 0.71 | ALDH1A1 (0.59) | KDM4EMAPTSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL17068947 | 0.71 | ALDH1A1 (0.59) | KDM4EMAPTSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL30322896 | 0.71 | MEN1 (0.47) | KDM4EMAPTSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL69894 | 0.71 | MEN1 (0.47) | KDM4EMAPTSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL11829286 | 0.70 | GABRG2 (0.55) | KDM4EMAPTSMN1; SMN2MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979943-A | 3-fluoro-5H-indeno [1,2-b ] pyridine compound and synthetic method thereof | 台州学院 | 2022-01-28 | — | — | CN | claimed |
| CN-113979943-A | 3-fluoro-5H-indeno [1,2-b ] pyridine compound and synthetic method thereof | 台州学院 | 2022-01-28 | — | — | CN | disclosed |
| CN-113979943-A | 3-fluoro-5H-indeno [1,2-b ] pyridine compound and synthetic method thereof | 台州学院 | 2022-01-28 | — | — | CN | disclosed |
| CN-113979943-A | 3-fluoro-5H-indeno [1,2-b ] pyridine compound and synthetic method thereof | 台州学院 | 2022-01-28 | — | — | CN | disclosed |