Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | AHR | P35869 | 1/20 | 0.72 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | HTR2C | P28335 | 3/20 | 0.62 |
| ▸ | HTR1D | P28221 | 2/20 | 0.62 |
| ▸ | HTR1B | P28222 | 2/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole-3-Carbinol SCHEMBL195520 | 1.00 | MEN1 (0.72) | MEN1KMT2AMAPTCYP3A4AHR | |
| Indole-3-Carbinol SCHEMBL29350358 | 1.00 | MEN1 (0.72) | MEN1KMT2AMAPTCYP3A4AHR | |
| Indole-3-Carbinol SCHEMBL30082813 | 0.98 | MEN1 (0.69) | MEN1KMT2AMAPTCYP3A4AHR | |
| Indole-3-Carbinol SCHEMBL63995 | 0.98 | MEN1 (0.69) | MEN1KMT2AMAPTCYP3A4AHR | |
| Indole-3-Carbinol SCHEMBL28474632 | 0.89 | MEN1 (0.63) | MEN1KMT2AMAPTCYP3A4AHR | |
| Indole-3-Carbinol SCHEMBL28164722 | 0.89 | MEN1 (0.58) | MEN1KMT2AMAPTCYP3A4AHR | |
| Indole-3-Carbinol SCHEMBL14119930 | 0.86 | AHR (0.57) | MEN1KMT2AMAPTCYP3A4AHR | |
| Tryptophol SCHEMBL29364545 | 0.85 | HTR2A (0.67) | MEN1KMT2AMAPTCYP3A4AHR | |
| Tryptophol SCHEMBL196126 | 0.85 | HTR2A (0.67) | MEN1KMT2AMAPTCYP3A4AHR | |
| Arundine SCHEMBL325162 | 0.84 | MEN1 (1.00) | MEN1KMT2AMAPTCYP3A4AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010124257-A2 | METHODS AND KITS FOR DETERMINING OXYGEN FREE RADICAL (OFR) LEVELS IN ANIMAL AND HUMAN TISSUES AS A PROGNOSTIC MARKER FOR CANCER AND OTHER PATHOPHYSIOLOGIES | COLBY PHARMACEUTICAL COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |
| US-20030190381-A1 | Medical composition for balancing bodily processes | METAGENICS, INC. | 2003-10-09 | — | — | US | disclosed |