Tryptophol

Tryptophol

SCHEMBL196126

OCCc1c[nH]c2ccccc12

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.67
CYP3A4 P08684 3/20 0.67
HTR2C P28335 3/20 0.67
CYP1A2 P05177 3/20 0.67
CYP2D6 P10635 2/20 0.67
HTR6 P50406 2/20 0.67
MPO P05164 1/20 0.67
CYP2A6 P11509 1/20 0.67
NFKB1 P19838 1/20 0.67
HTR1D P28221 1/20 0.67
HTR1B P28222 1/20 0.67
HTR7 P34969 1/20 0.67
CTSK P43235 1/20 0.67
CYP2A13 Q16696 1/20 0.67
TAAR1 Q96RJ0 1/20 0.67
PMP22 Q01453 1/20 0.65
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
MAPT P10636 1/20 0.64
AHR P35869 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophol SCHEMBL29364545 1.00 HTR2A (0.67) HTR2ACYP3A4HTR2CCYP1A2CYP2D6
Tryptophol SCHEMBL15619233 0.94 HTR2A (0.61) HTR2ACYP3A4HTR2CCYP1A2CYP2D6
Tryptophol SCHEMBL21682597 0.90 MEN1 (0.64) HTR2ACYP3A4HTR2CCYP1A2CYP2D6
SCHEMBL734588 0.89 SLC6A4 (0.63) HTR2ACYP3A4HTR2CCYP1A2CYP2D6
SCHEMBL31366243 0.89 SLC6A4 (0.63) HTR2ACYP3A4HTR2CCYP1A2CYP2D6
Tryptophol SCHEMBL649225 0.88 CYP1A2 (0.58) HTR2ACYP3A4HTR2CCYP1A2CYP2D6
SCHEMBL4985934 0.87 HTR2A (0.77) HTR2ACYP3A4HTR2CCYP1A2CYP2D6
Indolylpropionic Acid SCHEMBL195854 0.87 MAPT (0.61) CYP1A2MEN1KMT2AMAPTALDH1A1
Tryptophol SCHEMBL28616327 0.87 HTR2A (0.53) HTR2ACYP3A4HTR2CCYP1A2CYP2D6
SCHEMBL734204 0.87 SLC6A4 (0.61) HTR2ACYP3A4HTR2CCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1839 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4739326-A2 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR Biome ApS (DK) 2026-05-13 EP claimed
US-20260125689-A1 Novel Nuclear Localization Sequence Mutant and Method for Improving Biosynthetic Efficiency Using Same UNIV JIANGNAN (CN) 2026-05-07 US claimed
US-12576115-B2 Bacterial compositions for treating and preventing halitosis Imvela Corp. (US) 2026-03-17 US claimed
US-20260062554-A1 Stabilized Indigo Carmine Composition KINNOS INC (US) 2026-03-05 US claimed
US-20260053887-A1 Methods and Kits to Prevent And/Or Treat Cardiac Disorders UNIV IOWA RES FOUND (US) 2026-02-26 US claimed
EP-4688653-A2 MANUFACTURING OF HYBRID ORGANIC-INORGANIC SILICA AEROGELS AEROBEL BV (BE) 2026-02-11 EP claimed
US-20260027161-A1 BACTERIAL STRAINS FOR TREATING DISEASE MICROBA IP PTY LTD (AU) 2026-01-29 US claimed
US-20260028562-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION DANSTAR FERMENT AG (CH) 2026-01-29 US claimed
EP-3833366-B1 MICROORGANISM MIXTURES, MOLECULES DERIVED THEREFROM, AND METHODS OF USE THEREOF B G NEGEV TECHNOLOGIES AND APPLICATIONS LTD AT BEN GURION UNIV (IL) 2025-12-03 EP claimed
US-4826994-A FROM ISATIN AMERICAN HOME PRODUCTS CORPORATION (US) 1989-05-02 US claimed
US-4824961-A Production of substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids AMERICAN HOME PRODUCTS CORPORATION (US) 1989-04-25 US claimed
US-4822893-A Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids AMERICAN HOME PRODUCTS (US) 1989-04-18 US claimed
EP-0306149-A2 Substituted 1,3,4,9-tetrahydropyrano [3,4-b]indole-1-acetic acids AMERICAN HOME PRODUCTS CORPORATION (US) 1989-03-08 EP claimed
EP-0122151-B1 PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-02-15 EP claimed
US-4783402-A Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1988-11-08 US claimed
EP-0282951-A2 Controlled release preparations of active materials NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-09-21 EP claimed
EP-0279548-A1 Substituted 1,3,4,9-tetrahydropyrano [3,4-b] indole-1-acetic acids AMERICAN HOME PRODUCTS CORPORATION (US) 1988-08-24 EP claimed
EP-0238226-A1 Substituted 1,3,4,9-tetrahydropyrano [3,4-b]indole-1-acetic acids AMERICAN HOME PRODUCTS CORPORATION (US) 1987-09-23 EP claimed
EP-0122151-A2 Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1984-10-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062554-A1 Stabilized Indigo Carmine Composition SOD1, SOD3, SCO2 HTR2A 2100/4885CYP3A4 306/4885HTR2C 1619/4885
US-12576115-B2 Bacterial compositions for treating and preventing halitosis MAFK, MAFG, HVCN1 HTR2A 4086/4885CYP3A4 2329/4885HTR2C 3182/4885
US-20260125689-A1 Novel Nuclear Localization Sequence Mutant and Method for Improving Biosynthetic Efficiency Using Same NXF1, NDC1, FBL HTR2A 4542/4885CYP3A4 1862/4885HTR2C 4751/4885
US-20260053887-A1 Methods and Kits to Prevent And/Or Treat Cardiac Disorders KYNU, AADAT, TPH1 HTR2A 303/4885CYP3A4 751/4885HTR2C 520/4885
US-20260027161-A1 BACTERIAL STRAINS FOR TREATING DISEASE VIP, SI, ALPI HTR2A 4853/4885CYP3A4 2993/4885HTR2C 4488/4885
US-20260028562-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION CD69, SORD, TAS2R13 HTR2A 1384/4885CYP3A4 1977/4885HTR2C 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.