Methylene Chloride

Methylene Chloride

SCHEMBL28679574

Cc1ccc(O)c([N+](=O)[O-])c1.ClCCl

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
CYP3A4 P08684 1/20 0.58
GPR35 Q9HC97 3/20 0.55
MAPK1 P28482 2/20 0.55
ALDH1A1 P00352 2/20 0.55
TP53 P04637 1/20 0.55
HPGD P15428 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
KCNMA1 Q12791 2/20 0.50
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
MAPT P10636 3/20 0.49
KDM4E B2RXH2 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL306096 0.93 TSHR (0.67) TSHRCYP3A4GPR35MAPK1ALDH1A1
Hydrochloric Acid SCHEMBL11468634 0.91 TSHR (0.64) TSHRCYP3A4GPR35MAPK1ALDH1A1
Methoxymethane SCHEMBL5798314 0.87 TSHR (0.60) TSHRCYP3A4GPR35MAPK1ALDH1A1
P-Cresol SCHEMBL11753373 0.86 TSHR (0.58) TSHRCYP3A4GPR35MAPK1ALDH1A1
2,4-Dinitrophenol SCHEMBL27745042 0.80 GPR35 (0.85) TSHRGPR35MAPK1ALDH1A1TP53
SCHEMBL9318661 0.78 TSHR (0.54) TSHRCYP3A4GPR35MAPK1ALDH1A1
SCHEMBL31096484 0.77 TSHR (0.67) TSHRCYP3A4GPR35MAPK1ALDH1A1
SCHEMBL56264 0.77 TSHR (0.67) TSHRCYP3A4GPR35MAPK1ALDH1A1
Morpholine SCHEMBL27985030 0.77 TSHR (0.47) TSHRCYP3A4GPR35MAPK1ALDH1A1
SCHEMBL5500201 0.77 GPR35 (0.51) TSHRCYP3A4GPR35MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121356-B Automatic power continuous nitration method and device 中化安全科学研究(沈阳)有限公司 2022-06-14 CN disclosed
CN-113121356-A Automatic power continuous nitration method and device 中化安全科学研究(沈阳)有限公司 2021-07-16 CN disclosed