SCHEMBL5500201

SCHEMBL5500201

Cc1ccc(O)c([N+](=O)[O-])c1.O=[N+]([O-])c1cc([N+](=O)[O-])c2ccccc2c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 3/20 0.51
CTSB P07858 2/20 0.51
KMT2A Q03164 5/20 0.48
ALDH1A1 P00352 4/20 0.48
MAPT P10636 4/20 0.48
MEN1 O00255 4/20 0.48
KDM4E B2RXH2 2/20 0.48
GAA P10253 1/20 0.48
IDO1 P14902 1/20 0.48
TDO2 P48775 1/20 0.48
CASP6 P55212 1/20 0.48
TSHR P16473 3/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
KCNMA1 Q12791 1/20 0.46
LMNA P02545 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458 0.84 CASP6 (0.62) GPR35CTSBKMT2AALDH1A1MAPT
SCHEMBL29401731 0.84 CASP6 (0.62) GPR35CTSBKMT2AALDH1A1MAPT
SCHEMBL1740621 0.83 CASP6 (0.61) GPR35CTSBKMT2AALDH1A1MAPT
SCHEMBL1740623 0.83 CASP6 (0.61) GPR35CTSBKMT2AALDH1A1MAPT
SCHEMBL306096 0.83 TSHR (0.67) GPR35KMT2AALDH1A1MAPTKDM4E
SCHEMBL8947890 0.82 ALDH1A1 (0.62) GPR35CTSBKMT2AALDH1A1MAPT
Hydrochloric Acid SCHEMBL11468634 0.81 TSHR (0.64) GPR35ALDH1A1MAPTKDM4EGAA
Sulfuric Acid SCHEMBL11438972 0.79 TDP1 (0.67) GPR35CTSBKMT2AALDH1A1MAPT
Methoxymethane SCHEMBL5798314 0.78 TSHR (0.60) GPR35ALDH1A1MAPTKDM4EGAA
P-Cresol SCHEMBL11753373 0.77 TSHR (0.58) GPR35ALDH1A1MAPTKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817271-A1 AROMATIC SULFONIC ACIDS, AMINES, AND NITROPHENOLS IN COMBINATION WITH NITROXYL RADICAL-CONTAINING COMPOUNDS OR C-NITROSANILINES AS POLYMERIZATION INHIBITORS Chemtura Corporation (US) 2007-08-15 EP disclosed
WO-2006062563-A1 AROMATIC SULFONIC ACIDS, AMINES, AND NITROPHENOLS IN COMBINATION WITH NITROXYL RADICAL-CONTAINING COMPOUNDS OR C-NITROSANILINES AS POLYMERIZATION INHIBITORS CHEMTURA CORPORATION (US) 2006-06-15 WO disclosed