Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30232741 | 0.83 | CYP2C19 (0.59) | CYP2C19CYP1A2GAAP4HTMKMT2A | |
| SCHEMBL18160680 | 0.83 | CYP2C19 (0.48) | CYP2C19CYP1A2GAAADRA2AADRA2B | |
| SCHEMBL1403615 | 0.83 | CYP2C19 (0.59) | CYP2C19CYP1A2GAAP4HTMKMT2A | |
| SCHEMBL5326143 | 0.81 | ALDH1A1 (0.53) | CYP2C19CYP1A2GAAADRA2AADRA2B | |
| SCHEMBL17673994 | 0.81 | CYP2C19 (0.49) | CYP2C19CYP1A2GAAADRA2AADRA2B | |
| SCHEMBL18557889 | 0.80 | CYP1A2 (0.50) | CYP2C19CYP1A2GAAADRA2AADRA2B | |
| SCHEMBL3313819 | 0.80 | MAPT (0.60) | CYP2C19CYP1A2GAAKMT2AMAPT | |
| SCHEMBL15956178 | 0.80 | CYP2C19 (0.55) | CYP2C19CYP1A2GAAADRA2AADRA2B | |
| SCHEMBL1403645 | 0.79 | P4HTM (0.61) | CYP2C19CYP1A2GAAADRA2AADRA2B | |
| SCHEMBL9098551 | 0.79 | P4HTM (0.61) | CYP2C19CYP1A2GAAADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113853371-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113853371-A | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2021-12-28 | — | — | CN | disclosed |