Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 16/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 15/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28466498 | 0.88 | NR1H2 (0.57) | NR1H2NR1H3GPR119 | |
| SCHEMBL22957338 | 0.87 | GPR119 (0.51) | NR1H2NR1H3MEN1CYP2C19KMT2A | |
| SCHEMBL28690516 | 0.83 | NR1H2 (0.48) | NR1H2NR1H3MEN1CYP2C19KMT2A | |
| SCHEMBL28691536 | 0.82 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL28931799 | 0.79 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL30741110 | 0.79 | PARP1 (0.44) | NR1H2NR1H3 | |
| SCHEMBL29707313 | 0.79 | NR1H2 (0.43) | NR1H2NR1H3MEN1CYP2C19KMT2A | |
| SCHEMBL19212323 | 0.79 | MAPT (0.60) | MEN1CYP2C19KMT2ASMN1; SMN2GPR119 | |
| SCHEMBL28687960 | 0.77 | NR1H2 (0.51) | NR1H2NR1H3GPR119 | |
| SCHEMBL28693254 | 0.76 | NR1H2 (0.49) | NR1H2NR1H3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |