Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 17/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 16/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680705 | 0.85 | MAPT (0.50) | HTTSMN1; SMN2NPSR1NAMPT | |
| SCHEMBL28466498 | 0.78 | NR1H2 (0.57) | NR1H2NR1H3 | |
| SCHEMBL28690516 | 0.76 | NR1H2 (0.48) | NR1H2NR1H3HTTSMN1; SMN2NPSR1 | |
| SCHEMBL28679751 | 0.76 | NR1H2 (0.52) | NR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL19212238 | 0.72 | MAPT (0.42) | HTTSMN1; SMN2NPSR1 | |
| SCHEMBL28687960 | 0.72 | NR1H2 (0.51) | NR1H2NR1H3 | |
| SCHEMBL28931799 | 0.71 | NR1H2 (0.51) | NR1H2NR1H3NAMPT | |
| SCHEMBL83999 | 0.70 | GPR119 (0.48) | NR1H2NR1H3SMN1; SMN2NAMPT | |
| SCHEMBL1673508 | 0.69 | GPR119 (0.48) | NR1H2NR1H3NAMPT | |
| SCHEMBL1673505 | 0.69 | GPR119 (0.48) | NR1H2NR1H3NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |