Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322165 | 0.78 | MAPT (0.40) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL42875 | 0.76 | MAPT (0.36) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL29386113 | 0.76 | MAPT (0.36) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL29592639 | 0.75 | KMT2A (0.33) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL12727641 | 0.75 | POLB (0.49) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL992708 | 0.72 | KMT2A (0.56) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL300884 | 0.71 | CA12 (0.42) | KMT2AMEN1MAPTKDM4ERAB9A | |
| 2-Mercaptopyridine SCHEMBL28724071 | 0.71 | SMN1; SMN2 (0.39) | KMT2AMEN1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL10070313 | 0.70 | ALDH1A1 (0.37) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL19309377 | 0.70 | KMT2A (0.53) | KMT2AMAPTPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340607-A | anti-CD 166 antibodies, activatable anti-CD 166 antibodies, and methods of use thereof | 西托姆克斯治疗公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-107849133-B | anti-CD 166 antibodies, activatable anti-CD 166 antibodies, and methods of use thereof | 西托姆克斯治疗公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114907446-A | Matrix metalloprotease cleavable and serine protease cleavable substrates and methods of use thereof | 西托姆克斯治疗公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114716513-A | Matrix metalloprotease cleavable and serine protease cleavable substrates and methods of use thereof | 西托姆克斯治疗公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114685611-A | Matrix metalloprotease cleavable and serine protease cleavable substrates and methods of use thereof | 西托姆克斯治疗公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685661-A | Matrix metalloprotease cleavable and serine protease cleavable substrates and methods of use thereof | 西托姆克斯治疗公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114591433-A | anti-PD-1 antibodies, activatable anti-PD-1 antibodies, and methods of use thereof | 西托姆克斯治疗公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114507283-A | anti-CD 71 antibodies, activatable anti-CD 71 antibodies, and methods of use thereof | 西托姆克斯治疗公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114478704-A | Matrix metalloprotease cleavable and serine protease cleavable substrates and methods of use thereof | 西托姆克斯治疗公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-108368170-B | anti-PD-1 antibodies, activatable anti-PD-1 antibodies, and methods of use thereof | 西托姆克斯治疗公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-108026170-B | anti-CD 71 antibodies, activatable anti-CD 71 antibodies, and methods of use thereof | 西托姆克斯治疗公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-107531758-B | Matrix metalloprotease cleavable and serine protease cleavable substrates and methods of use thereof | 西托姆克斯治疗公司 | 2022-02-11 | — | — | CN | disclosed |