SCHEMBL300884

SCHEMBL300884

O=C(ON1C(=O)CCC1=O)c1ccc(C(=O)ON2C(=O)CCC2=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA9 Q16790 2/20 0.42
ALDH1A1 P00352 4/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 5/20 0.41
MGLL Q99685 2/20 0.40
MEN1 O00255 2/20 0.39
LMNA P02545 1/20 0.39
PARL Q9H300 1/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
RAB9A P51151 1/20 0.36
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA14 Q9ULX7 1/20 0.34
GLA P06280 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13455758 0.94 SMN1; SMN2 (0.44) CA12CA1CA9ALDH1A1HPGD
SCHEMBL5648489 0.92 CA12 (0.47) CA12CA1CA9ALDH1A1HPGD
SCHEMBL27717830 0.92 CA1 (0.55) CA12CA1CA9ALDH1A1HPGD
SCHEMBL159204 0.91 KDM4E (0.42) CA1ALDH1A1HPGDKMT2AMGLL
SCHEMBL16005095 0.91 ALDH1A1 (0.37) CA12CA1CA9ALDH1A1HPGD
SCHEMBL1696262 0.91 KDM4E (0.42) CA1ALDH1A1HPGDKMT2AMGLL
SCHEMBL3565689 0.91 MAPT (0.42) CA12CA1CA9ALDH1A1HPGD
SCHEMBL12216547 0.91 LMNA (0.44) CA12CA1CA9ALDH1A1HPGD
SCHEMBL1800956 0.91 PTPRF (0.44) CA1ALDH1A1HPGDLMNASMN1; SMN2
SCHEMBL317627 0.91 PTPN2 (0.44) CA12CA1CA9ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 EP disclosed
WO-2023239906-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2023-12-14 WO disclosed
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-11-09 US disclosed
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-11-09 US disclosed
US-20230310551-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2023-10-05 US disclosed
US-20230310551-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2023-10-05 US disclosed
EP-4204441-A1 INSULIN RECEPTOR PARTIAL AGONISTS Merck Sharp & Dohme LLC (US) 2023-07-05 EP disclosed
WO-2022046739-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME CORP. (US) 2022-03-03 WO disclosed
US-20210340276-A1 COMPLEX HAVING ANTI-HUMAN MUC1 ANTIBODY FAB FRAGMENT, PEPTIDE LINKER AND/OR LIGAND ASTELLAS PHARMA INC. (JP) 2021-11-04 US disclosed
US-10913743-B2 Use of organic oxyimides as flame retardant for plastic materials and also flame-retardant plastic material composition and moulded parts produced therefrom Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-02-09 US disclosed
EP-0803377-A1 Recording material FUJI PHOTO FILM CO., LTD. (JP) 1997-10-29 EP disclosed
US-5047308-A Microencapsulationof diazo compound or coupler FUJI PHOTO FILM CO., LTD. (JP) 1991-09-10 US disclosed
US-5028580-A Heat sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-02 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-4990482-A Transparent FUJI PHOTO FILM CO., LTD. (JP) 1991-02-05 US disclosed
US-4956251-A Multilayer, multicolor recording media, radiation transparent protective coatings FUJI PHOTO FILM CO., LTD. (JP) 1990-09-11 US disclosed
US-4929411-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US disclosed
US-4857941-A Multicolor thermal recording device FUJI PHOTO FILM CO., LTD. (JP) 1989-08-15 US disclosed
US-4547445-A WATERPROOF SUPPORT OF POLYOLEFIN COATED PAPER; ONE SIDE CONTAINS PHOTOGRAPHIC EMULSION; OTHER A HARDENED, PIGMENTED FUJI PHOTO FILM CO., LTD. (JP) 1985-10-15 US disclosed
US-4232117-A HYDROPHILIC COLLOID LAYERS CONTAINING GELATIN, MATTING AGENT, COLLOIDAL SILICA AND POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1980-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE SNRPE, DDX21, DCLRE1B CA12 4333/4885CA1 4028/4885CA9 4178/4885
US-20210340276-A1 COMPLEX HAVING ANTI-HUMAN MUC1 ANTIBODY FAB FRAGMENT, PEPTIDE LINKER AND/OR LIGAND MUC1, SIGLEC7, CA14 CA12 6/4885CA1 165/4885CA9 223/4885
US-10913743-B2 Use of organic oxyimides as flame retardant for plastic materials and also flame-retardant plastic material composition and moulded parts produced therefrom ORMDL3, OGDH, FTO CA12 2921/4885CA1 2945/4885CA9 3099/4885
US-20230310551-A1 INSULIN RECEPTOR PARTIAL AGONISTS INSR, GPR119, IRS1 CA12 4655/4885CA1 4717/4885CA9 4721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.