Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858417 | 0.91 | TNF (0.58) | TNFALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL5958908 | 0.81 | ALDH1A1 (0.55) | TNFALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL29144184 | 0.80 | TNF (0.49) | TNFALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL30049141 | 0.80 | TNF (0.49) | TNFALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL2278593 | 0.80 | TNF (0.47) | TNFALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL24813373 | 0.80 | TNF (0.49) | TNFALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL2280493 | 0.80 | TNF (0.47) | TNFALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL6233523 | 0.79 | NPC1 (0.41) | TNFALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL15930057 | 0.79 | ALDH1A1 (0.64) | TNFALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL2167750 | 0.79 | ALDH1A1 (0.64) | TNFALDH1A1MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651334-B | Process for preparing substituted piperidinedione derivatives | 南京卡文迪许生物工程技术有限公司 | 2021-12-21 | — | — | CN | disclosed |