Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL28680315

O=C(O)CCC(=O)ON1C(=O)CCC1=O.OCCOCCO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
KDM6B O15054 1/20 0.30
KDM5C P41229 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2467342 0.90 PSMB8 (0.35) PSMB8PSMB5KMT2AKDM6BKDM5C
SCHEMBL3521348 0.89 TSHR (0.34) PSMB8PSMB5TSHRMAPK1MEN1
SCHEMBL43575 0.88 EGLN1 (0.36) PSMB8PSMB5MAPK1KMT2AKDM6B
SCHEMBL16549691 0.87 MEN1 (0.37) PSMB8PSMB5TSHRMAPK1MEN1
SCHEMBL22047210 0.87 MEN1 (0.37) PSMB8PSMB5TSHRMAPK1MEN1
SCHEMBL15178462 0.87 MEN1 (0.37) PSMB8PSMB5TSHRMAPK1MEN1
SCHEMBL28680314 0.86 EPHX2 (0.34) PSMB8PSMB5TSHRMAPK1MEN1
SCHEMBL5092849 0.86 TSHR (0.33) PSMB8PSMB5TSHRMAPK1MEN1
Urea SCHEMBL4909809 0.86 PSMB8 (0.34) PSMB8PSMB5KDM6BKDM5CEGLN1
SCHEMBL17701607 0.85 KMT2A (0.33) PSMB8PSMB5KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113528612-B NicE-C technology for detecting chromatin interaction between chromatin open sites 中国科学技术大学 2023-03-14 CN claimed
CN-113528612-A NicE-C technology for detecting chromatin interaction between chromatin open sites 中国科学技术大学 2021-10-22 CN claimed
CN-118599974-A Nucleic acid enrichment method, chromatin interaction analysis method and kit 深圳华大基因股份有限公司 2024-09-06 CN disclosed
CN-113528612-B NicE-C technology for detecting chromatin interaction between chromatin open sites 中国科学技术大学 2023-03-14 CN disclosed
CN-113528612-A NicE-C technology for detecting chromatin interaction between chromatin open sites 中国科学技术大学 2021-10-22 CN disclosed