SCHEMBL43575

SCHEMBL43575

O=C(O)CCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.36
KDM6B O15054 1/20 0.36
KDM5C P41229 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
LMNA P02545 3/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
PSMB8 P28062 2/20 0.35
PSMB5 P28074 1/20 0.35
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
MGLL Q99685 3/20 0.33
ALOX12 P18054 1/20 0.32
PARL Q9H300 1/20 0.32
ALDH1A1 P00352 3/20 0.31
PKM P14618 1/20 0.31
MAPK1 P28482 1/20 0.30
HPGD P15428 1/20 0.30
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL7956362 0.94 EGLN1 (0.37) EGLN1KDM6BKDM5CPHF8KDM2A
Ethylene Glycol SCHEMBL2467342 0.94 PSMB8 (0.35) EGLN1KDM6BKDM5CPHF8KDM2A
Sulfuric Acid SCHEMBL12813397 0.93 PARL (0.35) EGLN1KDM6BKDM5CPHF8KDM2A
Propionic Acid SCHEMBL29510501 0.93 EGLN1 (0.36) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL31121824 0.92 LMNA (0.36) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL43576 0.92 PSMB8 (0.35) LMNAPSMB8PSMB5KMT2AATM
Succinimide SCHEMBL28277646 0.90 CRBN (0.35) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL2589620 0.90 PSMB8 (0.34) EGLN1KDM6BKDM5CPHF8KDM2A
Urea SCHEMBL4909809 0.90 PSMB8 (0.34) EGLN1KDM6BKDM5CPHF8KDM2A
Phloroglucinol SCHEMBL5216851 0.90 PSMB8 (0.36) EGLN1KDM6BKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5770 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4104853-B1 ARGININE DEIMINASE WITH REDUCED CROSS-REACTIVITY TOWARD ADI - PEG 20 ANTIBODIES FOR CANCER TREATMENT POLARIS GROUP (KY) 2026-05-06 EP claimed
EP-4683964-A2 POLY(ETHYLENE GLYCOL) BASED DENDRIMER-LIKE HYPERBRANCHED MACROMOLECULES, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2026-01-28 EP claimed
EP-4667566-A1 ARGININE DEIMINASE MUTANT, COVALENT DIMER AND CONJUGATE AND USE THEREOF Peg-Bio Biopharm Co., Ltd. (Chongqing) (CN) 2025-12-24 EP claimed
EP-4665307-A1 BIODEGRADABLE MICROPARTICLES FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2025-12-24 EP claimed
EP-4630058-A2 CHEMICAL TISSUE ABLATION WITH HYDROGEL MATRIX AND CORRESPONDING MEDICAL APPLICATIONS Pramand LLC (US) 2025-10-15 EP claimed
US-20250295792-A1 POLYETHYLENE GLYCOL-MODIFIED FORM OF KININ OR DERIVATIVE THEREOF AND PHARMACEUTICAL USE THEREOF ZONHON BIOPHARMA INSTITUTE, INC. (CN) 2025-09-25 US claimed
EP-4582090-A2 COMPOSITION COMPRISING PEGYLATED ARGININE DEIMINASE Polaris Group (TW) 2025-07-09 EP claimed
US-20250215414-A1 COMBINATION CANCER IMMUNOTHERAPIES WITH ARGININE DEPLETION AGENTS POLARIS GROUP (KY) 2025-07-03 US claimed
EP-4568658-A1 ORGANOGELS FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2025-06-18 EP claimed
CN-119258268-B Hydrogel band-aid for bone repair and preparation method and application thereof 山东大学 2025-05-30 CN claimed
WO-1998031383-A1 MODIFIED TUMOR NECROSIS FACTOR PHOENIX PHARMACOLOGICS, INC. (US) 1998-07-23 WO claimed
US-5711944-A Interferon polymer conjugates ENZON, INC. (US) 1998-01-27 US claimed
EP-0730470-A1 IMPROVED INTERFERON POLYMER CONJUGATES ENZON, INC. (US) 1996-09-11 EP claimed
CN-1126441-A Amplification of vitamin B12 absorption System Using polymers BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN claimed
WO-1995013090-A1 IMPROVED INTERFERON POLYMER CONJUGATES ENZON, INC. (US) 1995-05-18 WO claimed
US-5264209-A Polyoxyethylene glycol modified interleukin derivative for hematopoietic disorders and thrombocytopenia KIRIN-AMGEN, INC. (US) 1993-11-23 US claimed
EP-0442724-A2 Modified hIL-6 Kirin-Amgen, Inc. (US) 1991-08-21 EP claimed
US-4608246-A Testing for a blood group immunological reaction IMMUCOR, INC. (US) 1986-08-26 US claimed
EP-0157797-A1 DETECTING AN IMMUNOLOGICAL REACTION WITH ACTIVATED RED BLOOD CELLS (ERYTHROCYTES) IMMUCOR, INC. (US) 1985-10-16 EP claimed
WO-1985001354-A1 DETECTING AN IMMUNOLOGICAL REACTION WITH ACTIVATED RED BLOOD CELLS (ERYTHROCYTES) IMMUCOR, INC. (US) 1985-03-28 WO claimed