Urea

Urea

SCHEMBL4909809

NC(N)=O.O=C(O)CCC(=O)ON1C(=O)CCC1=O.OCCO

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.34
PSMB5 P28074 1/20 0.34
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2467342 0.95 PSMB8 (0.35) PSMB8PSMB5KDM6BKDM5CEGLN1
Urea SCHEMBL4916163 0.91 GPR84 (0.36) PSMB8PSMB5
Urea SCHEMBL4905652 0.91 TSHR (0.37) PSMB8PSMB5
SCHEMBL43575 0.90 EGLN1 (0.36) PSMB8PSMB5KDM6BKDM5CEGLN1
Thioglycolic Acid SCHEMBL27511458 0.89 PSMB8 (0.33) PSMB8PSMB5KDM6BKDM5CEGLN1
Ethylene Glycol SCHEMBL999673 0.88 PSMB8 (0.36) PSMB8PSMB5
Urethane SCHEMBL4909069 0.87 ALOX15 (0.40) PSMB8PSMB5
Di(Hydroxyethyl)Ether SCHEMBL28680315 0.86 PSMB8 (0.33) PSMB8PSMB5KDM6BKDM5CEGLN1
Ethylene Glycol SCHEMBL6129445 0.85 TSHR (0.40) PSMB8PSMB5
Methoxymethane SCHEMBL7956362 0.85 EGLN1 (0.37) PSMB8PSMB5KDM6BKDM5CEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US claimed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP claimed
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US disclosed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same KRT18, CUTA, KRTCAP2 PSMB8 1560/4885PSMB5 1049/4885KDM6B 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.