Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437401 | 0.85 | KMT2A (0.50) | SMN1; SMN2SLC6A2SLC6A3ALDH1A1MEN1 | |
| SCHEMBL10172754 | 0.85 | ALDH1A1 (0.60) | KDM4ESMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL11839840 | 0.85 | RAB9A (0.46) | KDM4ESMN1; SMN2NPC1MAPTHTT | |
| Hydrochloric Acid SCHEMBL11839850 | 0.83 | RAB9A (0.45) | KDM4ESMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL18415701 | 0.81 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL13429420 | 0.81 | ALDH1A1 (0.40) | SMN1; SMN2SLC6A2SLC6A3ALDH1A1MEN1 | |
| SCHEMBL13544220 | 0.80 | EPHX2 (0.43) | KDM4ESMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL13373425 | 0.80 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL2297635 | 0.80 | PARP10 (0.54) | KDM4ENPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL143772 | 0.79 | MEN1 (0.61) | KDM4ESLC6A2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710660-A | DOT1L degradation agent and application thereof | 达纳-法伯癌症研究公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-103282073-A | Urinary device | VYSERA BIOMEDICAL LTD | 2013-09-04 | — | — | CN | disclosed |