Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147712 | 0.97 | KCNN4 (0.52) | KCNN4TAAR1SLC6A2CYP1A2CYP2D6 | |
| Iodide SCHEMBL28805520 | 0.95 | KCNN4 (0.50) | KCNN4TAAR1SLC6A2CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL317557 | 0.95 | KCNN4 (0.50) | KCNN4TAAR1SLC6A2CYP1A2CYP2D6 | |
| SCHEMBL6307824 | 0.86 | MAPT (0.44) | KCNN4TAAR1SLC6A2CYP1A2CYP2D6 | |
| Ethylbenzene SCHEMBL5698698 | 0.86 | TP53 (0.61) | KCNN4TAAR1SLC6A2CYP1A2KIF11 | |
| Phosphoric Acid SCHEMBL27396881 | 0.84 | PTPN1 (0.47) | KCNN4TAAR1CYP1A2CYP2D6KIF11 | |
| SCHEMBL5999709 | 0.84 | KIF11 (0.49) | KCNN4TAAR1SLC6A2KIF11MAPT | |
| SCHEMBL18660794 | 0.84 | CYP2C19 (0.44) | KCNN4TAAR1SLC6A2CYP1A2CYP2D6 | |
| Bromide SCHEMBL11663273 | 0.82 | KCNN4 (0.48) | KCNN4TAAR1SLC6A2CYP1A2CYP2D6 | |
| SCHEMBL2837864 | 0.81 | PTPN1 (0.43) | KCNN4TAAR1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113991045-B | Pure blue perovskite light-emitting layer, preparation method thereof and light-emitting diode | 苏州大学 | 2024-02-02 | — | — | CN | claimed |
| CN-113991045-A | Pure blue light perovskite luminescent layer, preparation method thereof and light emitting diode | 苏州大学 | 2022-01-28 | — | — | CN | claimed |
| CN-113991045-B | Pure blue perovskite light-emitting layer, preparation method thereof and light-emitting diode | 苏州大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-113991045-A | Pure blue light perovskite luminescent layer, preparation method thereof and light emitting diode | 苏州大学 | 2022-01-28 | — | — | CN | disclosed |