Hydrochloric Acid

Hydrochloric Acid

SCHEMBL317557

CCC(N)(c1ccccc1)c1ccccc1.Cl

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.41
KCNN4 O15554 4/20 0.50
TAAR1 Q96RJ0 2/20 0.46
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPK1 P28482 1/20 0.39
KIF11 P52732 2/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
TP53 P04637 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147712 0.97 KCNN4 (0.52) KCNN4TAAR1SLC6A2CYP1A2CYP2D6
Iodide SCHEMBL28805520 0.95 KCNN4 (0.50) KCNN4TAAR1SLC6A2CYP1A2CYP2D6
Bromide SCHEMBL28680752 0.95 KCNN4 (0.50) KCNN4TAAR1SLC6A2CYP1A2CYP2D6
SCHEMBL6307824 0.86 MAPT (0.44) KCNN4TAAR1SLC6A2CYP1A2CYP2D6
Ethylbenzene SCHEMBL5698698 0.86 TP53 (0.61) KCNN4TAAR1SLC6A2CYP1A2KIF11
SCHEMBL18660794 0.84 CYP2C19 (0.44) KCNN4TAAR1SLC6A2CYP1A2CYP2D6
Phosphoric Acid SCHEMBL27396881 0.84 PTPN1 (0.47) KCNN4TAAR1CYP1A2CYP2D6KIF11
SCHEMBL5999709 0.84 KIF11 (0.49) KCNN4TAAR1SLC6A2KIF11MAPT
Hydrochloric Acid SCHEMBL890979 0.82 KCNN4 (0.48) KCNN4TAAR1SLC6A2CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL28250965 0.82 KCNN4 (0.48) KCNN4TAAR1SLC6A2CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 EP disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 EP disclosed
EP-1993741-B1 INLINE APPLICATION OF COATINGS COOK MEDICAL TECHNOLOGIES LLC (US) 2014-03-19 EP disclosed
US-8523937-B2 Controlled drug delivery using a zein layer modified with levulinic acid COOK MEDICAL TECHNOLOGIES LLC (US) 2013-09-03 US disclosed
US-8092819-B2 Implantable medical device coated with a bioactive agent Cook Medical Technologies LLC. (US) 2012-01-10 US disclosed
US-8024851-B2 Method of producing a radially expandable prosthesis COOK MEDICAL TECHNOLOGIES LLC (US) 2011-09-27 US disclosed
US-7914841-B2 Inline application of coatings COOK MEDICAL TECHNOLOGIES LLC (US) 2011-03-29 US disclosed
EP-1981560-B1 ZEIN COATED MEDICAL DEVICE MED INST INC (US) 2010-09-08 EP disclosed
US-20090258050-A1 Controlled Drug Delivery Using a Zein Layer Modified with Levulinic Acid MED INSTITUTE, INC. (US) 2009-10-15 US disclosed
US-20080178459-A1 METHOD OF PRODUCING A RADIALLY EXPANDABLE PROSTHESIS COOK INCORPORATED (US) 2008-07-31 US disclosed
US-20070299518-A1 Device with nanocomposite coating for controlled drug release MED INSTITUTE, INC. (US) 2007-12-27 US disclosed
US-20070207184-A1 Implantable medical device coated with a bioactive agent MED INSTITUTE, INC (US) 2007-09-06 US disclosed
US-20070207183-A1 Zein coated medical device MED INSTITUTE, INC. (US) 2007-09-06 US disclosed
US-20070196423-A1 Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent MED INSTITUTE, INC. (US) 2007-08-23 US disclosed
US-20070182055-A1 Inline application of coatings COOK INCORPORATED (US) 2007-08-09 US disclosed
US-20070043423-A1 Intraluminal device with a hollow structure MED INSTITUTE INC. (US) 2007-02-22 US disclosed
EP-0251339-A2 N6- substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same WARNER-LAMBERT COMPANY (US) 1988-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258050-A1 Controlled Drug Delivery Using a Zein Layer Modified with Levulinic Acid LTN1, LOXL2, LOXL1 SLC6A2 2718/4885KCNN4 4696/4885TAAR1 3454/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL SLC6A2 2491/4885KCNN4 4088/4885TAAR1 4220/4885
US-20070207183-A1 Zein coated medical device PCSK9, ZYX, ZFX SLC6A2 2846/4885KCNN4 4214/4885TAAR1 3099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.