SCHEMBL28680784

SCHEMBL28680784

Fc1c(Br)c2c(c(-c3ccccc3)c1-c1ccccc1)Cc1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
SQOR Q9Y6N5 2/20 0.35
MAP3K9 P80192 1/20 0.35
MAP3K11 Q16584 1/20 0.35
MAPK1 P28482 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
PNMT P11086 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 2/20 0.31
BCHE P06276 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29730500 0.79 MAP3K9 (0.46) KDRADORA2AADORA1SQORMAP3K9
SCHEMBL28145785 0.79 MAP3K9 (0.46) KDRADORA2AADORA1SQORMAP3K9
SCHEMBL31123421 0.79 MAP3K9 (0.46) KDRADORA2AADORA1SQORMAP3K9
SCHEMBL2359259 0.73 KDR (0.41) KDRADORA2AADORA1SQORMAP3K9
SCHEMBL8031980 0.73 ADORA2A (0.49) KDRADORA2AADORA1SQORMAP3K9
SCHEMBL18774731 0.73 MAP3K9 (0.46) KDRADORA2AADORA1MAP3K9MAP3K11
SCHEMBL8622497 0.72 MAP3K9 (0.42) KDRADORA2AADORA1MAP3K9MAP3K11
SCHEMBL8982031 0.71 PNMT (0.43) KDRADORA2AADORA1SQORMAP3K9
SCHEMBL18337985 0.71 KDR (0.42) KDRADORA2AADORA1SQORMAP3K9
SCHEMBL24623524 0.71 ALDH1A1 (0.40) MAPK1ALDH1A1ACHEMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113841262-A Organic light emitting device 株式会社LG化学 2021-12-24 CN disclosed