Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28693363 | 1.00 | OPRM1 (0.46) | OPRM1LAP3SPHK1SGPL1S1PR2 | |
| SCHEMBL28685635 | 1.00 | OPRM1 (0.46) | OPRM1LAP3SPHK1SGPL1S1PR2 | |
| SCHEMBL28102742 | 0.91 | — | — | |
| SCHEMBL28183052 | 0.83 | — | — | |
| SCHEMBL13637149 | 0.79 | SGPL1 (0.44) | OPRM1LAP3SGPL1LMNA | |
| SCHEMBL21827757 | 0.79 | SGPL1 (0.44) | OPRM1LAP3SGPL1LMNA | |
| SCHEMBL30965148 | 0.79 | SGPL1 (0.51) | OPRM1LAP3SGPL1LMNA | |
| SCHEMBL14848265 | 0.79 | SGPL1 (0.44) | OPRM1LAP3SGPL1LMNA | |
| SCHEMBL15524956 | 0.79 | SGPL1 (0.44) | OPRM1LAP3SGPL1LMNA | |
| SCHEMBL28664154 | 0.79 | SGPL1 (0.44) | OPRM1LAP3SGPL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113788795-B | Water-soluble aggregation-induced emission nanoparticle and preparation method and application thereof | 广东省科学院生物与医学工程研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-113788795-A | Water-soluble aggregation-induced emission nanoparticle and preparation method and application thereof | 广东省科学院生物与医学工程研究所 | 2021-12-14 | — | — | CN | disclosed |