Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212041 | 0.87 | PTGDR2 (0.51) | PTGDR2MAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL22957446 | 0.83 | SMN1; SMN2 (0.50) | PTGDR2MAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13193091 | 0.82 | MGLL (0.51) | PTGDR2RORCSYKMAPTSMN1; SMN2 | |
| SCHEMBL7043026 | 0.78 | POLB (0.62) | SYKMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19210898 | 0.78 | LMNA (0.52) | MAPTSMN1; SMN2NPC1LMNAIDO1 | |
| SCHEMBL28687598 | 0.78 | LMNA (0.52) | MAPTSMN1; SMN2LMNAIDO1HTT | |
| SCHEMBL29707309 | 0.78 | LMNA (0.52) | MAPTSMN1; SMN2NPC1LMNAIDO1 | |
| SCHEMBL6560301 | 0.78 | LMNA (0.52) | MAPTSMN1; SMN2LMNAIDO1HTT | |
| SCHEMBL6680791 | 0.78 | NQO2 (0.44) | MAPTSMN1; SMN2ALDH1A1LMNAIDO1 | |
| SCHEMBL27493607 | 0.78 | NQO2 (0.44) | MAPTSMN1; SMN2ALDH1A1TP53IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414252-B1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO HEALTH INC (US) | 2022-07-06 | — | — | EP | disclosed |
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |