Morpholine

Morpholine

SCHEMBL28680895

C1COCCN1.C=CCNC(=S)Nc1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
MAPT P10636 3/20 0.52
MAPK1 P28482 1/20 0.52
GAA P10253 3/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
PKM P14618 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1647857 0.84 ALDH1A1 (0.69) ALDH1A1MAPTMAPK1GAAMEN1
Morpholine SCHEMBL11370089 0.74 TGM2 (0.67) LMNAMAOAMAOBPOLB
SCHEMBL28667396 0.74 GAA (0.63) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL28667398 0.74
SCHEMBL31459385 0.73 LSS (0.59) ALDH1A1MAPTMAPK1GAAMEN1
SCHEMBL9779693 0.71 GAA (0.67) ALDH1A1MAPTGAAMEN1KMT2A
Morpholine SCHEMBL9304115 0.71 CYP2C19 (0.51) ALDH1A1MAPTGAALMNAPOLB
SCHEMBL28667400 0.70 ALDH1A1 (0.65) ALDH1A1MAPTMAPK1GAAMEN1
SCHEMBL5450539 0.70 MAPT (0.71) ALDH1A1MAPTMAPK1GAAMEN1
SCHEMBL2236429 0.70 GAA (0.66) ALDH1A1MAPTMAPK1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113831559-A Method for improving interfacial adhesion performance of epoxy resin-based composite material 浙江省开化七一电力器材有限责任公司 2021-12-24 CN disclosed