Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | FNTA | P49354 | 5/20 | 0.34 |
| ▸ | FNTB | P49356 | 5/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16972949 | 0.86 | RORC (0.39) | MDM2RORC | |
| SCHEMBL16972952 | 0.86 | RORC (0.39) | MDM2RORC | |
| SCHEMBL16968531 | 0.74 | MEN1 (0.42) | FNTAFNTBRORCESR2 | |
| SCHEMBL30139745 | 0.74 | MEN1 (0.42) | FNTAFNTBRORCESR2 | |
| SCHEMBL16972920 | 0.72 | RORC (0.45) | RORC | |
| SCHEMBL16972921 | 0.72 | RORC (0.45) | RORC | |
| SCHEMBL16977424 | 0.71 | BACE1 (0.34) | FNTAFNTB | |
| SCHEMBL17688603 | 0.71 | HRH4 (0.34) | MDM2P2RX7 | |
| SCHEMBL12094922 | 0.70 | AOC3 (0.65) | AOC3 | |
| SCHEMBL1973686 | 0.70 | AOC3 (0.65) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463458-B | Modulators of ROR-gamma | 生命医药有限责任公司 | 2022-02-01 | — | — | CN | disclosed |