Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696297 | 0.81 | HEXA (0.41) | CYP1B1KDM4EHTR1ADRD2HTR2A | |
| SCHEMBL28684148 | 0.81 | KDM4E (0.44) | KDM4EHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL28689910 | 0.80 | HTR1A (0.44) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL28695945 | 0.79 | HTR1A (0.43) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL28703527 | 0.78 | BCHE (0.38) | CYP1B1KDM4EALDH1A1MAPTAPAF1 | |
| SCHEMBL8555421 | 0.69 | SLC6A2 (0.47) | KDM4ESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL8559698 | 0.68 | TDP1 (0.48) | KDM4ESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL8559794 | 0.68 | TDP1 (0.48) | KDM4ESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL8559087 | 0.68 | TDP1 (0.48) | KDM4ESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL8558048 | 0.68 | TDP1 (0.48) | KDM4ESLC6A2SLC6A4SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665987-B | Naphthaleneimide-polyamine conjugates, methods of making and uses thereof | 河南大学 | 2022-02-18 | — | — | CN | disclosed |