Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 11/20 | 0.44 |
| ▸ | HTR7 | P34969 | 10/20 | 0.44 |
| ▸ | DRD2 | P14416 | 10/20 | 0.44 |
| ▸ | HTR6 | P50406 | 10/20 | 0.44 |
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689910 | 0.92 | HTR1A (0.44) | HTR1AHTR7DRD2HTR6HTR2A | |
| SCHEMBL28695945 | 0.92 | HTR1A (0.43) | MEN1KMT2AHTR1AHTR7DRD2 | |
| SCHEMBL28696297 | 0.85 | HEXA (0.41) | KDM4EALDH1A1HTR1AHTR7DRD2 | |
| SCHEMBL28693048 | 0.83 | HTR7 (0.44) | KDM4EMEN1ALDH1A1CASP1CASP7 | |
| SCHEMBL28703527 | 0.81 | BCHE (0.38) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL28684152 | 0.81 | CYP1B1 (0.33) | KDM4EMEN1ALDH1A1KMT2AHTR1A | |
| SCHEMBL28296691 | 0.74 | PARP1 (0.40) | HTR7PARP1 | |
| SCHEMBL28704987 | 0.67 | HEXA (0.41) | KDM4EMEN1ALDH1A1CASP1CASP7 | |
| SCHEMBL28684142 | 0.67 | PDE10A (0.43) | KDM4EALDH1A1HSD17B10HTR1AHTR7 | |
| SCHEMBL28704128 | 0.66 | CYP1B1 (0.60) | KDM4EMEN1ALDH1A1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665987-B | Naphthaleneimide-polyamine conjugates, methods of making and uses thereof | 河南大学 | 2022-02-18 | — | — | CN | disclosed |