SCHEMBL28685012

SCHEMBL28685012

Cc1cc2ccc1-2.N=C=O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.44
ESR1 P03372 2/20 0.44
HSD17B1 P14061 1/20 0.40
AKR1C3 P42330 3/20 0.38
AKR1C2 P52895 3/20 0.38
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PDE3B Q13370 6/20 0.35
PDE3A Q14432 6/20 0.35
MCL1 Q07820 1/20 0.34
FGFR1 P11362 1/20 0.34
PTGS2 P35354 2/20 0.33
SLC2A1 P11166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL4602569 0.82
SCHEMBL5334234 0.82
Bromide SCHEMBL28927015 0.82
Hydrogen Sulfide SCHEMBL28451021 0.82
SCHEMBL4011227 0.81 RXRA (0.37) ESR2ESR1CYP3A4MCL1PTGS2
SCHEMBL27898433 0.78 MCL1 (0.47) HSD17B1ALDH1A1CYP3A4TSHRTDP1
Acetic Acid SCHEMBL11041891 0.76 HSD17B1 (0.53) ESR2ESR1HSD17B1AKR1C3AKR1C2
Formic Acid SCHEMBL28050270 0.76 ESR2 (0.48) ESR2ESR1HSD17B1AKR1C3AKR1C2
SCHEMBL28695736 0.76 ESR2 (0.52) ESR2TDP1PDE3BPDE3A
SCHEMBL2350935 0.75 ESR2 (0.52) ESR2ESR1HSD17B1AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096949-A Polyurethane elastic fiber, gather member containing same, and sanitary material 旭化成株式会社 2023-05-09 CN disclosed
CN-110249084-B Polyurethane elastic fiber, method for producing same, and gather member comprising same 旭化成株式会社 2022-02-11 CN disclosed