Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23147830 | 0.87 | L3MBTL1 (0.51) | L3MBTL1BRD4CA1CA2PKM | |
| SCHEMBL29721803 | 0.87 | L3MBTL1 (0.51) | L3MBTL1BRD4CA1CA2PKM | |
| SCHEMBL30690865 | 0.82 | L3MBTL1 (0.47) | L3MBTL1BRD4CA1CA2RAPGEF4 | |
| SCHEMBL21354079 | 0.82 | L3MBTL1 (0.47) | L3MBTL1BRD4CA1CA2RAPGEF4 | |
| SCHEMBL28721164 | 0.82 | L3MBTL1 (0.49) | L3MBTL1BRD4CA1CA2PKM | |
| SCHEMBL29548843 | 0.82 | L3MBTL1 (0.49) | L3MBTL1BRD4CA1CA2PKM | |
| SCHEMBL21439101 | 0.81 | L3MBTL1 (0.46) | L3MBTL1BRD4CA1CA2PKM | |
| SCHEMBL21439147 | 0.81 | L3MBTL1 (0.46) | L3MBTL1BRD4CA1CA2RAPGEF4 | |
| SCHEMBL23762156 | 0.81 | L3MBTL1 (0.46) | L3MBTL1BRD4PKMALDH1A1MAPT | |
| SCHEMBL31246107 | 0.81 | L3MBTL1 (0.50) | L3MBTL1BRD4CA1CA2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183471-B | Piperazine derivative, preparation method and application | 江苏大学 | 2022-02-15 | — | — | CN | claimed |
| CN-110183471-B | Piperazine derivative, preparation method and application | 江苏大学 | 2022-02-15 | — | — | CN | disclosed |