Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426836 | 0.88 | L3MBTL1 (0.53) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL1015374 | 0.86 | L3MBTL1 (0.52) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL4724390 | 0.85 | L3MBTL1 (0.51) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL4793803 | 0.84 | L3MBTL1 (0.50) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL25273685 | 0.82 | L3MBTL1 (0.48) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL31052395 | 0.82 | L3MBTL1 (0.48) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL23147817 | 0.81 | L3MBTL1 (0.47) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL28685402 | 0.81 | L3MBTL1 (0.49) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL29548843 | 0.81 | L3MBTL1 (0.49) | L3MBTL1BRD4PKMCA1CA2 | |
| SCHEMBL28721164 | 0.81 | L3MBTL1 (0.49) | L3MBTL1BRD4PKMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4687883-A2 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024211249-A2 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2024-10-10 | — | — | WO | disclosed |