Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 7/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929972 | 0.90 | KMT2A (0.68) | KMT2ANR4A2PLA2G4BNR1H4MRGPRX4 | |
| SCHEMBL1665041 | 0.88 | KMT2A (0.73) | KMT2ANR4A2PLA2G4BNR1H4MRGPRX4 | |
| SCHEMBL30517635 | 0.88 | KMT2A (0.73) | KMT2ANR4A2PLA2G4BNR1H4MRGPRX4 | |
| SCHEMBL3148484 | 0.86 | KMT2A (0.66) | KMT2ANR4A2PLA2G4BNR1H4MRGPRX4 | |
| SCHEMBL1029366 | 0.84 | KDM4E (0.58) | PLA2G4BTP53PKM | |
| SCHEMBL11326622 | 0.84 | KMT2A (0.41) | KMT2A | |
| SCHEMBL2877777 | 0.83 | TDP1 (0.55) | KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2934559 | 0.83 | KMT2A (0.71) | KMT2ANR4A2PLA2G4BNR1H4MRGPRX4 | |
| SCHEMBL1503531 | 0.83 | PKM (0.56) | PLA2G4BRAB9ATP53PKMSMN1; SMN2 | |
| SCHEMBL19665046 | 0.81 | KMT2A (0.73) | KMT2ANR4A2PLA2G4BNR1H4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043866-A2 | HISTONE LYSINE DEMETHYLASE INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2010-04-22 | — | — | WO | disclosed |