SCHEMBL28685685

SCHEMBL28685685

CCCCNC1CC1.CO[SiH](OC)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.47
GNAO1 P09471 2/20 0.47
GNAI1 P63096 2/20 0.47
DRD2 P14416 3/20 0.40
DRD3 P35462 3/20 0.40
S1PR4 O95977 2/20 0.40
S1PR1 P21453 2/20 0.40
S1PR3 Q99500 2/20 0.40
CYP2C9 P11712 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
CNR1 P21554 2/20 0.38
CNR2 P34972 1/20 0.38
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
METAP1 P53582 1/20 0.35
S1PR5 Q9H228 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35
FUCA1 P04066 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1933458 0.87 GNAI3 (0.57) GNAI3GNAO1GNAI1DRD2DRD3
SCHEMBL1678660 0.87
SCHEMBL7520334 0.80 KCNH2 (0.40) GNAI3GNAO1GNAI1DRD2DRD3
SCHEMBL21089248 0.80 GNAI3 (0.52) GNAI3GNAO1GNAI1DRD2DRD3
SCHEMBL530708 0.80
SCHEMBL17222443 0.79 KDM4E (0.35) GNAI3GNAO1GNAI1DRD2DRD3
SCHEMBL13999315 0.78 GNAI3 (0.50) GNAI3GNAO1GNAI1DRD2DRD3
SCHEMBL24210534 0.78 GNAI3 (0.70) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL20746945 0.78 GNAI3 (0.70) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL9155873 0.78 GNAI3 (0.70) GNAI3GNAO1GNAI1S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109666115-B Amino silane end-capped modified polyurethane resin and preparation method thereof 万华化学集团股份有限公司 2021-09-07 CN claimed
CN-115259167-A Vacuum continuous modification process and device 巩义市泛锐熠辉复合材料有限公司 2022-11-01 CN disclosed