SCHEMBL7520334

SCHEMBL7520334

CCNC1CC1.CO[SiH](OC)OC

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.40
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
METAP1 P53582 1/20 0.31
GNAI3 P08754 2/20 0.31
GNAO1 P09471 2/20 0.31
GNAI1 P63096 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25042763 0.82 KCNH2 (0.52) KCNH2DRD2DRD4DRD3METAP1
SCHEMBL1142602 0.82 KCNH2 (0.52) KCNH2DRD2DRD4DRD3METAP1
SCHEMBL549384 0.82
SCHEMBL28685685 0.80 GNAI3 (0.47) DRD2DRD3CYP1A2CYP2D6CYP2C19
SCHEMBL1996565 0.80 KCNH2 (0.50) KCNH2
Ammonia Solution, Strong SCHEMBL3924276 0.79
Hydrochloric Acid SCHEMBL1643106 0.79
Hydrochloric Acid SCHEMBL28286507 0.79
SCHEMBL12473180 0.76 KCNH2 (0.40) KCNH2DRD2DRD4DRD3
SCHEMBL6923302 0.76 KCNH2 (0.40) KCNH2DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866734-B1 METHOD AND COMPOSITION USEFUL FOR TREATING METAL SURFACES CHEMAT TECHNOLOGY INC (US) 2002-03-06 EP claimed