Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 3/20 | 0.57 |
| ▸ | FNTA | P49354 | 5/20 | 0.42 |
| ▸ | FNTB | P49356 | 5/20 | 0.42 |
| ▸ | CCR1 | P32246 | 7/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506803 | 1.00 | EZH2 (0.57) | EZH2FNTAFNTBCCR1KDM5B | |
| SCHEMBL29846416 | 0.78 | EZH2 (0.51) | EZH2ALOX15TRPV1 | |
| SCHEMBL2594393 | 0.78 | EZH2 (0.51) | EZH2ALOX15TRPV1 | |
| SCHEMBL15687571 | 0.78 | CYP11B2 (0.56) | EZH2CCR1 | |
| SCHEMBL2587384 | 0.77 | EZH2 (0.50) | EZH2TRPV1 | |
| SCHEMBL28264532 | 0.76 | EZH2 (0.47) | EZH2CCR1TRPV1 | |
| SCHEMBL30122893 | 0.73 | EZH2 (1.00) | EZH2 | |
| SCHEMBL12684416 | 0.73 | EZH2 (1.00) | EZH2 | |
| SCHEMBL29846604 | 0.72 | EZH2 (0.51) | EZH2CCR1 | |
| SCHEMBL27419359 | 0.71 | PLK1 (0.60) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999211-B | Indazole skeleton derivative containing 1,2,3-triazole with specific activity of resisting prostate cancer | 郑州大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113999211-A | Indazole skeleton derivatives containing 1,2, 3-triazole and having specific activity of resisting prostate cancer | 郑州大学 | 2022-02-01 | — | — | CN | disclosed |