SCHEMBL28686557

SCHEMBL28686557

CC(O[SiH3])c1ccc(B2OC(C)(C)C(C)(C)O2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
LPL P06858 12/20 0.47
LIPG Q9Y5X9 12/20 0.47
ESR2 Q92731 1/20 0.47
CA12 O43570 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
F11 P03951 2/20 0.40
P4HB P07237 1/20 0.35
AAK1 Q2M2I8 1/20 0.35
F2 P00734 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16177602 0.84 LPL (0.49) CA1CA2CA9LPLLIPG
SCHEMBL3320459 0.84 LPL (0.49) CA1CA2CA9LPLLIPG
SCHEMBL31353179 0.84 LPL (0.49) CA1CA2CA9LPLLIPG
SCHEMBL87138 0.80 LIPG (0.55) CA1CA2CA9LPLLIPG
SCHEMBL3676367 0.78 ESR2 (0.43) CA1CA2CA9LPLLIPG
SCHEMBL17129595 0.78 CA1 (0.47) CA1CA2CA9LPLLIPG
SCHEMBL28371250 0.77 LIPG (0.57) CA1CA2CA9LPLLIPG
SCHEMBL228212 0.77 LPL (0.71) CA1CA2CA9LPLLIPG
SCHEMBL24775237 0.77 LIPG (0.52) CA1CA2CA9LPLLIPG
SCHEMBL19110515 0.77 LPL (0.52) CA1CA2CA9LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113825748-A Antimicrobial compounds and methods 库扎环球有限责任公司 2021-12-21 CN disclosed