Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.39 |
| ▸ | HTT | P42858 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | MITF | O75030 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008524 | 0.81 | ALDH1A1 (0.48) | CNR2RAB9AHTTNPC1MITF | |
| SCHEMBL28704815 | 0.79 | RAB9A (0.37) | RAB9ANPC1SMN1; SMN2KMT2ACA12 | |
| SCHEMBL25366576 | 0.76 | CNR2 (0.59) | CNR2RAB9AHTTNPC1MITF | |
| SCHEMBL28692963 | 0.73 | CDK4 (0.30) | — | |
| SCHEMBL10704992 | 0.72 | CNR2 (0.45) | CNR2RAB9AHTTNPC1MITF | |
| SCHEMBL31574319 | 0.71 | CNR2 (0.46) | CNR2RAB9AHTTNPC1MITF | |
| SCHEMBL9376742 | 0.70 | CNR2 (0.45) | CNR2RAB9AHTTNPC1MITF | |
| SCHEMBL9376739 | 0.69 | CNR2 (0.44) | CNR2RAB9AHTTNPC1MITF | |
| SCHEMBL15566620 | 0.67 | CNR2 (0.59) | CNR2RAB9AHTTNPC1MITF | |
| SCHEMBL13267231 | 0.67 | ALDH1A1 (0.46) | CNR2LMNAALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939295-A | Pyridazinones and methods of use thereof | 金翅雀生物公司 | 2022-01-14 | — | — | CN | disclosed |