Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697178 | 0.88 | GPR119 (0.49) | GPR119CNR1STSTACR1PARP1 | |
| SCHEMBL19212180 | 0.85 | GPR119 (0.51) | GPR119CNR1STSTP53SMN1; SMN2 | |
| SCHEMBL29707348 | 0.85 | GPR119 (0.51) | GPR119CNR1STSTP53SMN1; SMN2 | |
| SCHEMBL18617599 | 0.77 | TACR1 (0.48) | GPR119STSTACR1JAK2JAK1 | |
| SCHEMBL20672066 | 0.75 | TACR1 (0.49) | GPR119STSTACR1JAK2JAK1 | |
| SCHEMBL17595292 | 0.74 | PDE4B (0.55) | GPR119STSTACR1TP53JAK2 | |
| SCHEMBL18618119 | 0.74 | PDE4B (0.55) | GPR119STSTACR1TP53JAK2 | |
| SCHEMBL19092639 | 0.74 | GPR119 (0.51) | GPR119TP53DPP4SMN1; SMN2 | |
| SCHEMBL19212385 | 0.74 | STS (0.46) | GPR119CNR1STSTP53DPP4 | |
| SCHEMBL29707368 | 0.74 | STS (0.46) | GPR119CNR1STSTP53DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |