Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.51 |
| ▸ | STS | P08842 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212180 | 1.00 | GPR119 (0.51) | GPR119STSMAPTKDM4ETHRB | |
| SCHEMBL19212385 | 0.88 | STS (0.46) | GPR119STSMAPTKDM4ETHRB | |
| SCHEMBL29707368 | 0.88 | STS (0.46) | GPR119STSMAPTKDM4ETHRB | |
| SCHEMBL19212420 | 0.87 | GPR119 (0.54) | GPR119STSMAPTKDM4ETHRB | |
| SCHEMBL29707387 | 0.87 | GPR119 (0.54) | GPR119STSMAPTKDM4ETHRB | |
| SCHEMBL19092639 | 0.86 | GPR119 (0.51) | GPR119MAPTKDM4ETHRBSMN1; SMN2 | |
| SCHEMBL4786221 | 0.85 | CNR1 (0.56) | STSMAPTKDM4ETHRBSMN1; SMN2 | |
| SCHEMBL28689001 | 0.85 | GPR119 (0.46) | GPR119STSSMN1; SMN2CNR1TP53 | |
| SCHEMBL28673691 | 0.85 | GPR119 (0.49) | GPR119STSMAPTKDM4ETHRB | |
| SCHEMBL17398495 | 0.84 | ESR2 (0.52) | GPR119STSMAPTKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414252-B1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO HEALTH INC (US) | 2022-07-06 | — | — | EP | disclosed |